BNP (B-type Natriuretic Peptide)
The BNP (B-type Natriuretic Peptide) analysis is an advanced blood laboratory test used to assess heart condition. This test is often used for the diagnosis and monitoring of heart failure – a condition in which the heart cannot pump enough blood to meet the body’s needs.
What is BNP?
BNP is a hormone produced in the heart, mainly in the heart ventricles, and released into the bloodstream. When the heart is under stress, as is the case with heart failure, the level of BNP in the blood increases. By measuring BNP levels, experts at IntroLab laboratory in Belgrade can gain insight into how well the heart is performing its function.
Who is recommended for BNP analysis?
BNP serves as support in the diagnosis and monitoring of therapy for congestive heart failure. Therefore, BNP testing is recommended for individuals showing symptoms of congestive heart failure or those who have already been diagnosed with this disease, for the purpose of monitoring its progression.
It is recommended to use either NT-proBNP or BNP test for monitoring disease progression, but not both simultaneously.
Interpretation of results
Decreased BNP values may indicate the absence of congestive heart failure in a patient. However, it should be noted that medications such as ACE inhibitors, beta-blockers, and diuretics can lead to lower BNP levels.
In cases of acute congestive heart failure (within the first hour) or in patients with blood flow obstruction in the heart chambers (such as hypertrophic obstructive cardiomyopathy, heart valve stenosis, atrial myxoma), it has been noted that BNP may not necessarily be elevated.
Patients who have been exposed to animal-derived antigens, either from the external environment or during medical procedures like imaging with contrast agents, can develop antibodies that may interfere with BNP testing. This interference can lead to unreliable results.
On the other hand, if BNP levels are elevated, it may indicate heart failure, but the result is always interpreted by a doctor, as BNP can also be elevated in other conditions.
Sample and preparation: BNP (B-type Natriuretic Peptide)
- Sample
- Venous blood
- Sampling
- Drawing blood
- Result in
- 1 day
- Preparation
- No special preparation is required.
- Category
- Immunohemistry
Frequently asked questions
Do I need to prepare for a BNP test?
No, the BNP test requires no special preparation, and blood is taken from a vein in the arm. However, before the blood draw at IntroLab laboratory, tell your doctor or the staff which medications you are taking, as some drugs affect BNP levels: ACE inhibitors, beta-blockers and diuretics can lead to lower values. This is especially important when BNP is monitored during heart failure treatment.
How much does a BNP test cost and when is the result ready?
The BNP (B-type Natriuretic Peptide) test at IntroLab in Belgrade costs 3,500 RSD, and the result is ready in 1 day. Venous blood is drawn for the test, with no special preparation. BNP is most often done in people with symptoms of congestive heart failure, to support the diagnosis, or in those already diagnosed, to monitor disease progression and the effect of therapy.
What is the difference between the BNP and pro BNP tests?
BNP and NT-proBNP come from the same molecule that the heart releases when it is under strain: BNP is the active hormone, and NT-proBNP is the inactive part of the molecule that stays in the blood longer. Both are used to diagnose and monitor heart failure, but their values cannot be compared directly, so one of the two tests is used to monitor the disease, not both at the same time. At IntroLab laboratory, BNP costs 3,500 RSD and pro BNP costs 4,000 RSD.
What does elevated BNP mean?
Elevated BNP shows that the heart is under increased strain and most often points to heart failure. BNP can also be elevated in other conditions, for example kidney disease, atrial fibrillation, pulmonary embolism or older age, so the result alone is not enough for a diagnosis. Low values argue against heart failure, but some medications can also lower them. A BNP result from IntroLab laboratory is interpreted by a doctor, together with an examination and a heart ultrasound.