Urea Clearance: price and preparation | IntroLab Belgrade
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Urea Clearance

Price400 RSD
Result in4h
Sample24 urine
Urea Clearance test, IntroLab laboratory Belgrade Written byMilica Ranković Urea Clearance test, IntroLab laboratory Belgrade Medically reviewed byDr. Igor Švonja, MD

Published: Updated:

Urea clearance is a urine test that evaluates kidney function by measuring the kidneys’ ability to excrete urea. This test is a crucial indicator of kidney health and assists doctors in identifying and monitoring kidney-related diseases. It is available at IntroLab, a reputable private laboratory in Belgrade.

What is Urea Clearance?

Urea clearance measures how effectively the kidneys filter urea from the blood. Urea is a waste product produced when the body breaks down proteins. Healthy kidneys filter urea from the blood and excrete it in the urine. If the kidneys are not functioning properly, urea levels in the blood can rise, indicating a potential kidney issue.

Why is Measuring Urea Clearance Important?

Measuring urea clearance is crucial for diagnosing and monitoring kidney diseases. Kidney diseases can reduce the kidneys’ ability to filter urea, leading to elevated urea levels. This test helps identify kidney problems and allows doctors to evaluate the effectiveness of treatments for kidney disease.

Who Should Have This Biochemical Urine Analysis?

This test is recommended for individuals with symptoms or conditions that may indicate kidney disease. Symptoms include:

  • Fatigue
  • Loss of appetite
  • Nausea
  • Vomiting
  • Changes in urine output
  • Swelling of hands and feet

It is also indicated for those with conditions that increase the risk of kidney disease, such as diabetes, high blood pressure, or specific genetic disorders.

How are the Results Interpreted?

The results are evaluated considering the patient’s overall clinical picture, including other lab results and symptoms. Elevated urea levels in the blood can indicate kidney problems but may also result from conditions like dehydration, high protein intake, or certain liver diseases. Lower urea levels can be due to malnutrition, pregnancy, or specific genetic conditions.

How is the Test Performed?

The urea clearance test requires collecting a 24-hour urine sample.

Sample and preparation: Urea Clearance

Sample
24 urine
Sampling
Urine collection
Result in
4h
Preparation
Determine if you need one or more 2-liter bottles. Discard the first morning urine (do not collect it). Collect all urine produced throughout the day and night in the bottle. Include the first morning urine of the next day. Deliver the entire collected sample to the laboratory for analysis. For certain tests, a preservative must be added to the bottle first – ask the laboratory for specific instructions.
Category
Urine analysis

Frequently asked questions

How is a urea clearance test done and how much does it cost?

The Urea Clearance test at IntroLab laboratory requires 24-hour urine. Discard the first morning urine, then collect all urine during the day and night in the bottle, add the first morning urine of the next day and bring the entire amount to the laboratory. The test costs 400 RSD, and the result is ready in 4 hours. For some tests a preservative is first added to the bottle, so ask the laboratory about this in advance.

What is the difference between urea clearance and creatinine clearance?

Urea clearance and creatinine clearance are two tests that assess how well the kidneys clear waste products from the blood. Urea clearance shows how the kidneys excrete urea, a waste product of protein breakdown, while creatinine clearance follows the excretion of creatinine and is more often used to estimate glomerular filtration. Both tests are usually done from 24-hour urine. At IntroLab laboratory the Urea Clearance test costs 400 RSD, and a doctor decides which tests are needed.

What does low urea clearance mean?

Low urea clearance means that the kidneys excrete less urea than expected, which can be a sign of reduced kidney function. Kidney diseases lower their ability to filter urea, so it can build up in the blood. Still, the Urea Clearance result from IntroLab laboratory is interpreted together with other lab results and symptoms, because urea levels are also affected by hydration and protein intake. The interpretation and next steps are always decided by a doctor.

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