Methylmalonic Acid Test (Vitamin B12 Deficiency)
IntroLab in Belgrade offers a methylmalonic acid test, which is essential for monitoring the levels of this substance in the body. Methylmalonic acid plays a key role in the metabolism of certain proteins, and elevated levels can indicate potential health issues, such as vitamin B12 deficiency.
What is the connection between vitamin B12 and methylmalonic acid?
Methylmalonic acid is a biomarker used to detect vitamin B12 deficiency. Under normal conditions, vitamin B12 is necessary for the proper metabolism of methylmalonic acid. However, when there is a vitamin B12 deficiency, the enzyme responsible for converting methylmalonic acid into another substance is not adequately activated. This results in increased levels of methylmalonic acid in the body.
When to consider a methylmalonic acid (vitamin B12 deficiency) test
The methylmalonic acid test can be useful in the following situations. First, when there is a suspicion of vitamin B12 deficiency, elevated levels of methylmalonic acid in the blood can indicate this deficiency. Second, the methylmalonic acid test can be used to monitor the effectiveness of vitamin B12 therapy in patients with a deficiency, to determine whether the therapy is working and normalizing the levels of this acid. Of course, it is important that this blood test is performed with the expert evaluation of a doctor, considering the specific symptoms and needs of the patient.
Sample and preparation: Methylmalonic Acid Test (Vitamin B12 Deficiency)
- Sample
- Venous Blood
- Sampling
- Blood Draw
- Result in
- 15 days
- Preparation
- Fasting is required (no food or water intake for 8-12 hours) before sampling.
- Category
- Immunohemistry
Frequently asked questions
How much does a methylmalonic acid test cost?
The Methylmalonic Acid Test (MMA) at IntroLab laboratory costs 6,000 RSD, and results are ready in 15 days. It is done on venous blood, and you should fast for 8–12 hours before the blood draw. Doctors usually order it when vitamin B12 deficiency is suspected or when they want to check whether vitamin B12 therapy is working.
What does methylmalonic acid in the blood show?
Elevated methylmalonic acid in the blood may indicate vitamin B12 deficiency. Vitamin B12 is needed by the enzyme that converts methylmalonic acid into another substance, so when B12 is lacking, the enzyme does not work properly and the acid level rises. That is why the MMA test is used as a biomarker of vitamin B12 deficiency and to monitor the effectiveness of therapy. Results from IntroLab laboratory are interpreted by a doctor, together with symptoms and other findings.