{"id":8347,"date":"2023-05-14T17:16:11","date_gmt":"2023-05-14T17:16:11","guid":{"rendered":"https:\/\/introlab.net\/?page_id=8347"},"modified":"2026-01-20T16:34:46","modified_gmt":"2026-01-20T16:34:46","slug":"haptoglobin","status":"publish","type":"analiza","link":"https:\/\/introlab.net\/en\/haptoglobin\/","title":{"rendered":"Haptoglobin"},"content":{"rendered":"<p>At <a href=\"https:\/\/introlab.net\/en\/\">IntroLab<\/a>, a well-known biochemical laboratory in Belgrade, you can undergo a haptoglobin analysis to check its concentration in serum or plasma. <strong>Haptoglobin is an important protein that binds free hemoglobin, preventing the loss of iron from the body and kidney damage.<\/strong> Haptoglobin analysis is particularly useful for diagnosing hemolytic anemia, where a decreased concentration of haptoglobin is observed in patients with reduced erythrocyte lifespan.<!--more--><\/p>\n<h2>More about the parameter<\/h2>\n<p>Haptoglobin is a complex glycoprotein produced in the liver and <em>consists of two pairs of polypeptide chains, \u03b1 and \u03b2.<\/em> These chains are connected by disulfide bonds, forming an \u03b12\u03b22 structure. The \u03b1 polypeptide can be in two forms, \u03b11 and \u03b12. By combining \u03b11 and \u03b12 chains with the \u03b2 chain, three phenotypes of haptoglobin are formed: HAP 1-1 (\u03b11\u00b2\u03b22), HAP 2-1 (\u03b11\u03b12\u03b22), and HAP 2-2 (\u03b12\u00b2\u03b22).<\/p>\n<p>Haptoglobin plays a key role in binding free hemoglobin in the plasma. <strong>Each haptoglobin molecule can bind two hemoglobin molecules, forming a stable complex.<\/strong> This complex, known as Hp-Hgb, is removed from the plasma by cells of the reticuloendothelial system (RES), which catabolize it into amino acids and iron. In this way, haptoglobin prevents the excretion of hemoglobin through urine and the loss of iron.<\/p>\n<h2>Haptoglobin analysis &#8211; Indications<\/h2>\n<p>Indications for haptoglobin analysis include:<\/p>\n<ul>\n<li><strong>Suspicion of hemolytic anemia:<\/strong> The analysis is used for the diagnosis and monitoring of hemolytic anemias, which are characterized by a shortened lifespan of erythrocytes. Therefore, it is considered one of the key blood anemia analyses.<\/li>\n<li><strong>Liver function assessment:<\/strong> Changes in haptoglobin concentration can be an indicator of liver damage.<\/li>\n<li><strong>Monitoring therapy:<\/strong> The analysis is used to monitor the effectiveness of therapy and the body&#8217;s response to treatments that affect erythrocytes.<\/li>\n<\/ul>\n<p>Consult with a specialist or visit IntroLab laboratory in Belgrade to determine the level of haptoglobin. We will perform blood drawing for analysis so you can receive accurate information about your health condition.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>At IntroLab, a well-known biochemical laboratory in Belgrade, you can undergo a haptoglobin analysis to check its concentration in serum or plasma. Haptoglobin is an important protein that binds free hemoglobin, preventing the loss of iron from the body and kidney damage. Haptoglobin analysis is particularly useful for diagnosing hemolytic anemia, where a decreased concentration [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"template":"","kategorija-analize":[179],"vrsta-uzorka":[302,293],"tip-analize":[359],"class_list":["post-8347","analiza","type-analiza","status-publish","hentry","kategorija-analize-biochemistry","vrsta-uzorka-serum-en","vrsta-uzorka-venska-krv-en","tip-analize-pojedinacna-en"],"acf":{"cena":1200,"cena_prikaz":"cena","cena_napomena":"","obrtno_vreme":{"tip":"tacno","od":1,"do":"","jedinica":"dan","napomena":""},"uzorak":"Serum (venous blood)","uzorkovanje":"Drawing blood","priprema_tip":"posebna","priprema":"No special preparation is needed. However, it is not recommended to take the sample immediately after a meal.","stavke_panela":"","stavke_panela_ostalo":"","podnaslov":"","sinonimi":"","povezane_analize":null,"sifra":"","autor":null,"recenzent":null,"datum_pregleda":null},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Haptoglobin | IntroLab Belgrade<\/title>\n<meta name=\"description\" content=\"Haptoglobin analysis allows you to detect the presence of hemolytic anemia. 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