ROMA index

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0 rsd

Obrtno Vreme

4h

Uzorkovanje

Venipuncture

Kategorija

Immunohemistry

The ROMA index is utilized in IntroLab laboratories and offers precise determination of the probability of ovarian malignancy, providing essential information for further treatment and patient monitoring.

What does the ROMA index represent?

The ROMA index, or the Risk of Ovarian Malignancy Algorithm, is a mathematical model used to assess the likelihood of ovarian cancer in women. This model is based on measuring the concentration of two blood biomarkers – HE4 protein and Cancer Antigen 125 (CA 125). Considering a woman’s menopausal status and these values, the ROMA index provides an estimation of the risk of ovarian cancer. HE4 is a protein that is commonly found in high concentrations in women with epithelial ovarian cancer.

What is the purpose of measuring the ROMA index?

The ROMA index serves as a crucial tool in diagnosing and monitoring various diseases, as well as assessing the functionality of vital organs. It is particularly important in the context of epithelial ovarian carcinoma, where the HE4 protein is used in combination with CA-125 to monitor patients who have been treated for this type of cancer. For HE4 to be effective as a tumor marker, its concentration must be elevated before the start of treatment.

How are the results interpreted?

Based on the values of the ROMA index, an assessment is made as to whether the patient has ovarian cancer and whether they fall into the low or high-risk group for this disease. The reference interval is indicated on each validated report, and the values vary depending on whether the woman is in the pre or post-menopausal period. An elevated ROMA index value indicates a higher likelihood that the tumor is malignant. For pre-menopausal women, the value of this index should be less than 1.14 (indicating a low risk of ovarian malignancy), while for post-menopausal women, the value of this index should be below 2.99 (also indicating a low risk of ovarian malignancy).

Vrsta uzorka i vreme kada se uzima uzorak

Uzorak: Venous Blood

Obrtno vreme: 4h

Priprema: No special preparation is required.

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