Lymphocyte Subpopulations

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5130,00 rsd

Obrtno Vreme

Sampling on Tuesdays, 3 days

Uzorkovanje

Blood Draw

Kategorija

Hematology

Our expert team at IntroLab in Belgrade conducts analyses of lymphocyte subpopulations. This test may be recommended if there is a suspicion of an immune system disorder or to monitor the effects of therapy for certain diseases.

What are Lymphocyte Subpopulations?

Lymphocyte subpopulations refer to different types of lymphocytes, which are white blood cells that play a crucial role in the immune system. There are three main types of lymphocyte subpopulations:

  • T-lymphocytes (T-cells): These cells are named after the thymus, the organ where they mature. T-cells are essential for cellular immunity, protecting the body against pathogens such as viruses. T-cells are further divided into:
    • CD4+ T-lymphocytes (T-helper cells): These cells help activate other immune cells.
    • CD8+ T-lymphocytes (cytotoxic T-cells): These cells can destroy virus-infected cells.
  • B-lymphocytes (B-cells): B-cells mature in the bone marrow, which is where their name comes from. They are responsible for humoral immunity, producing antibodies that can neutralize pathogens like bacteria and viruses.
  • Natural Killer (NK) cells: These cells can directly destroy certain abnormal cells in the body, such as tumor cells or virus-infected cells.

Analyzing lymphocyte subpopulations helps doctors understand the state of a patient’s immune system, diagnose conditions, and monitor the effects of treatments for various diseases.

Why is Lymphocyte Subpopulation Test Performed?

Lymphocyte subpopulation test is typically conducted to assess the state of a patient’s immune system, particularly when there is a suspicion of certain immune disorders, infectious diseases, or malignancies.

Here are some specific reasons for performing this analysis:

  • Immunodeficiency: Individuals with weakened immune systems may experience changes in the number or function of their lymphocytes. This includes people with HIV/AIDS, where CD4+ T-lymphocytes are often monitored.
  • Autoimmune Diseases: Conditions such as lupus, rheumatoid arthritis, or multiple sclerosis can cause abnormalities in lymphocyte subpopulations.
  • Malignancies: Diseases like leukemia and lymphoma can lead to significant changes in the number and types of lymphocytes.
  • Infectious Diseases: Various infections, especially viral ones, can alter lymphocyte subpopulations. These changes can be temporary (as seen in acute infections) or permanent (as seen in chronic infections).
  • Assessment of Immune Response: This analysis can help evaluate how the body is responding to treatments such as vaccinations or immunotherapy.

It is important to note that lymphocyte subpopulation analysis alone is usually not sufficient for making a diagnosis. It is typically used in combination with other laboratory tests, physical examinations, and clinical information.

Preparation for the Analysis

No special preparation is required for this test. A blood sample is taken from a vein on the inside of your elbow.

Specifics and Subtypes of the Analysis

In addition to the standard lymphocyte subpopulation analysis, other tests can provide additional information. These include assessments of lymphocyte function and the detection of specific markers on the surface of the cells.

Vrsta uzorka i vreme kada se uzima uzorak

Uzorak: Venous Blood

Obrtno vreme: Sampling on Tuesdays, 3 days

Priprema: No special preparation is required for this analysis.

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