Gastrin

Your journey to good health begins at IntroLab.

2150,00 rsd

Obrtno Vreme

1 day

Uzorkovanje

Blood Draw

Kategorija

Immunohemistry

Gastrin is a key hormone in our body, and its analysis can provide valuable information about our health. This test, available at IntroLab in Belgrade, helps us better understand how our body functions and identify potential health issues before they become serious.

What is Gastrin?

Gastrin is a hormone produced by G cells in the antrum of the stomach. It plays a crucial role in our digestive system by stimulating the production of stomach acid, antral motility, secretion of pepsin, and intrinsic factor. There are two main forms of gastrin circulating in our blood: G-34, known as big gastrin, and G-14, known as minigastrin. Both of these polypeptides have a half-life of 5 minutes and can be found in both nonsulfated and sulfated forms.

Why is measuring Gastrin important?

Measuring gastrin is important because it allows us to monitor how our body responds to food. When we consume food, our stomach stretches and begins to stimulate the release of gastrin. Gastrin then stimulates the parietal cells to produce stomach acid, which helps in digesting food. As the acidity in the stomach increases, the release of gastrin decreases, resulting in lower concentrations of gastrin in the blood, especially when fasting. This feedback mechanism is crucial for the normal functioning of our digestive system.

However, there are rare conditions, such as G-cell hyperplasia and gastrinomas, including Zollinger-Ellison (ZE) syndrome, that can lead to increased production of gastrin and stomach acid. This can result in the development of peptic ulcers that are difficult to treat. Therefore, the gastrin test is essential for detecting these conditions.

When is a Gastrin test needed?

The gastrin test is primarily used to detect increased production of gastrin and stomach acid. There are specific cases when this test is particularly important:

  • If there is suspicion of a gastrinoma, a tumor that produces gastrin
  • Zollinger-Ellison syndrome, a condition characterized by high levels of gastrin in the blood, excessive production of stomach acid, and the development of peptic ulcers

Your doctor will recommend a gastrin test if there are symptoms or risk factors indicating the need for this test. These symptoms may include chronic stomach problems, heartburn, peptic ulcers, or other digestive issues. Additionally, the gastrin test may be part of a routine check-up for patients with certain hereditary syndromes or other medical conditions associated with abnormalities in gastrin production.

How are Gastrin test results interpreted?

Gastrin test results can provide valuable information about a person’s health. Moderately elevated gastrin levels can occur in certain situations, including:

  • Zollinger-Ellison syndrome: This condition is characterized by the presence of a gastrinoma, a tumor that produces gastrin. High levels of gastrin in the blood and increased production of stomach acid are typical symptoms of this syndrome.
  • G-cell hyperplasia: This condition refers to an abnormal increase in the number of G-cells in the antrum of the stomach, resulting in increased gastrin production.
  • Chronic atrophic gastritis: This type of gastritis is characterized by inflammation of the stomach lining and a decrease in the number of G-cells, which can lead to increased gastrin production.
  • Pernicious anemia: This is an autoimmune disease that leads to a deficiency of vitamin B12. The connection between pernicious anemia and elevated gastrin levels is still being researched.
  • Pyloric obstruction: The pylorus is the part of the stomach that regulates the passage of food into the small intestine. Pyloric obstruction can lead to increased gastrin production.
  • Hypersecretion of Basal Gastrin (HBG): This term describes a condition where the basal secretion of gastrin is elevated but not associated with a specific disease.

Extremely high levels of gastrin may be present in more serious conditions such as Zollinger-Ellison syndrome and gastrinoma. It is important to note that the concentration of gastrin in the blood is not directly related to the size of the tumor producing gastrin. Other factors such as symptoms, clinical presentation, and additional tests are considered when making a diagnosis.

On the other hand, low levels of gastrin do not have diagnostic significance. However, it is important to monitor and understand any changes in gastrin levels in the context of other symptoms and additional tests that the doctor may have recommended.

Vrsta uzorka i vreme kada se uzima uzorak

Uzorak: Venous Blood

Obrtno vreme: 1 day

Priprema: For the gastrin test at IntroLab in Belgrade, you should fast for at least 12 hours before the test and avoid coffee, caffeinated beverages, and alcohol for 24 hours beforehand. Additionally, consult with your doctor to stop taking certain stomach medications a few days prior to the test. Proper preparation ensures accurate results.

Analysis

Processing time

Price

Schedule an analysis

Analysis

Processing time

Price

Schedule an analysis

Analysis

Processing time

Price

Schedule an analysis

Analysis

Processing time

Price

Schedule an analysis

Analysis

Processing time

Price

Schedule an analysis

Analysis

Processing time

Price

Schedule an analysis

Analysis

Processing time

Price

Schedule an analysis

Analysis

Processing time

Price

Schedule an analysis

This site is registered on wpml.org as a development site.