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Cytomegalovirus IgG Avidity (CMV)

Price3.500 RSD
Result in8 days
SampleVenous Blood
PreparationNot required
Cytomegalovirus IgG Avidity (CMV) test, IntroLab laboratory Belgrade Written byDr. Igor Švonja, MD

Published: Updated:

The Cytomegalovirus IgG (CMV) avidity test is a diagnostic tool that provides important information about a patient’s health. At IntroLab in Belgrade, our expert team is committed to delivering accurate and reliable results for this and many other tests.

What is Cytomegalovirus IgG Avidity (CMV)?

Cytomegalovirus (CMV) is a common virus that can cause a wide range of symptoms, from mild to severe. When someone is initially infected with CMV, the immune system generates specific antibodies – IgM and IgG. Avidity measures the strength of the bond between these antibodies (IgG) and the CMV antigen. CMV IgG avidity testing helps doctors determine whether an infection is recent (low avidity) or older (high avidity).

Why is Cytomegalovirus IgG Avidity (CMV) measured?

Measuring CMV IgG avidity is important for several reasons:

  • Helps diagnose CMV infection: IgG avidity testing can distinguish between a recent primary infection and a past infection.
  • Essential for pregnant women: CMV can lead to complications if a first-time infection occurs during pregnancy. The avidity test assists doctors in determining the timing of the infection, which is critical for assessing the risk to the fetus.

When is this test necessary?

The Cytomegalovirus IgG (CMV) avidity test is typically recommended in the following cases:

  • When a patient shows symptoms that could suggest a CMV infection.
  • If a CMV IgM antibody test is positive, to determine if the infection is recent.
  • For pregnant women who test positive for CMV IgM, to assess whether the infection is recent.

How are the results interpreted?

Results of the CMV IgG avidity test are generally categorized as low, borderline, or high:

  • Low avidity typically indicates a recent, primary infection.
  • High avidity points to an older infection.
  • Borderline results may require a follow-up test.

A doctor should interpret the results in the context of the patient’s overall clinical picture and other laboratory findings.

Preparation for Cytomegalovirus IgG (CMV) Avidity test

No special preparation is necessary for this test. It’s important to inform your doctor about any medications you are taking, as they may influence the test results.

Test specifics and types

This test is often paired with other tests, such as CMV IgM and IgG antibody tests, to provide a comprehensive diagnosis and evaluation.

Sample and preparation: Cytomegalovirus IgG Avidity (CMV)

Sample
Venous Blood
Sampling
Blood Draw
Result in
8 days
Preparation
No special preparation is required.
Category
Immunology

Frequently asked questions

How much does the CMV IgG avidity test cost and when are results ready?

The Cytomegalovirus IgG Avidity (CMV) test at IntroLab laboratory costs 3,500 RSD, and the result is ready in 8 days. It is done from a venous blood sample and no specific preparation is needed, but you should tell your doctor which medications you are taking. The avidity test is not done on its own: it is interpreted together with IgM and IgG antibodies to CMV, most often when CMV IgM is positive, to determine whether the infection is recent.

What does high or low CMV IgG avidity mean?

High avidity of CMV IgG antibodies points to an older infection, and low avidity to a recent, primary cytomegalovirus infection. Avidity is the strength of the bond between IgG antibodies and the virus, so the test helps distinguish a recent infection from one that occurred earlier. A borderline result usually requires repeat testing. The IntroLab laboratory avidity result is interpreted by a doctor, together with the clinical picture and other laboratory results.

Why is CMV avidity tested in pregnancy?

In pregnancy it is important to know whether a CMV infection occurred before or during pregnancy, because cytomegalovirus can cause problems if the infection happens for the first time during pregnancy. A positive CMV IgG alone does not show this. The avidity test helps the doctor assess the timing of infection and the risk to the fetus: high avidity points to an older infection, and low avidity to a recent one. At IntroLab laboratory the test is done from venous blood, most often in pregnant women with positive CMV IgM.

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