APO-A-I

Your journey to good health begins at IntroLab.

550,00 rsd

Obrtno Vreme

1 day

Uzorkovanje

Drawing blood

Kategorija

Immunohemistry

The APO-A-I analysis is a laboratory test performed to assess the levels of apolipoprotein A-I in the blood. APO-A-I is a high-density lipoprotein (HDL) protein that plays a crucial role in the transport of cholesterol from peripheral tissue mass back to the liver for elimination. This blood analysis is important for assessing lipid status and the risk of cardiovascular diseases.

Apolipoprotein A-I (APO-A-I) is one of the high-density lipoproteins (HDL) proteins that play a key role in lipid metabolism. APO-A-I is synthesized in the small intestine and hepatocytes, and together with other apolipoproteins such as APO A-II, APO A-IV, APO E, and APO C, it forms the structure of HDL cholesterol. HDL cholesterol, which contains APO-A-I, has an important role in the reverse transport of cholesterol from peripheral tissues back to the liver, providing a protective effect in preventing atherosclerosis and cardiovascular diseases.

Biochemical analyses, like the APO-A-I analysis, are used for early detection, risk assessment, and diagnosis of certain hereditary diseases. The IntroLab laboratory in Belgrade provides precise results for measuring APO-A-I levels in the blood, enabling you to understand your lipid profile and heart health better. At the same time, the cost of a lipid status analysis is more than affordable.

APO-A-I analysis: Indications

The apolipoprotein A-I analysis is indicated in the following cases:

  • As part of a blood lipid status analysis
  • For a more detailed assessment of the causes of dyslipoproteinemias (changes in the composition and function of blood lipoproteins)
  • Particularly in patients with low levels of HDL cholesterol
  • For monitoring the effectiveness of anti-hyperlipidemic therapy (medications to lower cholesterol and lipid levels in the blood)

Interpretation of results

Low values of APO-A-I can be associated with reduced levels of HDL cholesterol. Therefore, they may indicate an increased risk of developing cardiovascular diseases. Additionally, decreased APO-A-I values may be present in hereditary disorders such as hypoalphalipoproteinemia and analphalipoproteinemia. These disorders are characterized by the body’s reduced ability to produce or transport certain types of apolipoproteins, which can lead to lipoprotein dysfunctionality and potentially increase the risk of heart diseases.

On the other hand, APO-A-I concentration can be increased in several situations. For example, familial hyperalphalipoproteinemia, a hereditary disorder, leads to high levels in the blood. During pregnancy, the concentration of apolipoprotein A-I may be increased as a natural adaptation of the body. Additionally, increased physical activity and the use of oral contraceptives can lead to higher values of APO-A-I.

Vrsta uzorka i vreme kada se uzima uzorak

Uzorak: Venous blood

Obrtno vreme: 1 day

Priprema: As part of the preparation, it is necessary to maintain your usual diet without changes in body weight for at least 14 days before the analysis. The patient should refrain from intense physical activities for at least 24 hours before sample collection. The blood sample is taken in the morning, after a fasting period of 10-12 hours.

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