ANA (ENA) Profile 15 At

At IntroLab in Belgrade, we offer a comprehensive range of tests, including the ANA(ENA) Profile 15 At analysis. This specialized immunological test is designed to detect specific autoantibodies in the blood.

What are extractable nuclear antigens?

Extractable nuclear antigens (ENAs) are a group of proteins located in the cell nucleus. These proteins are often targeted by autoantibodies—antibodies that mistakenly identify the body’s own cellular proteins as foreign and attack them. The presence of these autoantibodies in the blood can be indicative of certain autoimmune diseases.

Why is the ANA(ENA) profile 15 At test important?

This test is often used when autoimmune diseases are suspected, such as:

• Lupus
• Scleroderma
• Sjögren’s syndrome
• Polymyositis

This test helps in the precise diagnosis and monitoring of these diseases.

It should be conducted in individuals showing symptoms of autoimmune diseases, such as:

• Fatigue
• Joint pain
• Swelling
• Skin rash
• Dry mouth or eyes

Additionally, if you have already been diagnosed with an autoimmune disease, this test can help in monitoring the disease’s progression and the effectiveness of the therapy.

Specifics and subtypes of the test

The ANA(ENA) profile 15 At test can detect various types of autoantibodies in the blood, aiding in the identification of specific autoimmune diseases. For example, antibodies against Ro and La antigens are often found in Sjögren’s syndrome, while antibodies against the Sm antigen are specific to lupus. However, it is important to note that autoantibodies can be present in the blood without an autoimmune disease. Thus, the results of this test should be considered as part of a comprehensive clinical evaluation.